Amazing images captured by Eryn E. Dixon graced the cover of Nature Reviews Nephrology for an entire year!

GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD.
Dixon EE, Maxim DS, Halperin Kuhns VL, Lane-Harris AC, Outeda P, Ewald AJ, Watnick TJ, Welling PA, Woodward OM
J Cell Sci. 2020 Jul 16;133(14):jcs249557. doi: 10.1242/jcs.249557.
PMID: 32513820 Free PMC article.
  
The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion.
Hoque KM, Dixon EE, Lewis RM, Allan J, Gamble GD, Phipps-Green AJ, Halperin Kuhns VL, Horne AM, Stamp LK, Merriman TR, Dalbeth N, Woodward OM.
Nat Commun. 2020 Jun 2;11(1):2767. doi: 10.1038/s41467-020-16525-w.PMID: 32488095
PMID: 32488095 Free PMC article.
  
Sex Differences in Urate Handling.
Halperin Kuhns VL, Woodward OM.
Int J Mol Sci. 2020 Jun 16;21(12):4269. doi: 10.3390/ijms21124269.
PMID: 32560040 Free PMC article.
  
Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1.
Rodriguez S, Little HC, Daneshpajouhnejad P, Shepard BD, Tan SY, Wolfe A, Cheema MU, Jandu S, Woodward OM, Talbot CC Jr, Berkowitz DE, Rosenberg AZ, Pluznick JL, Wong GW.
FASEB J. 2020 Feb;34(2):2657-2676. doi: 10.1096/fj.201900558RR. Epub 2019 Dec 26.
PMID: 31908037 [PubMed – in process]
  
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, O’Connor LJ, Prins B, Nutile T, Noce D, Akiyama M, Cocca M, Ghasemi S, van der Most PJ, Horn K, Xu Y, Fuchsberger C, Sedaghat S, Afaq S, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boerwinkle E, Bottinger EP, Boutin TS, Brumat M, Burkhardt R, Campana E, Campbell A, Campbell H, Carroll RJ, Catamo E, Chambers JC, Ciullo M, Concas MP, Coresh J, Corre T, Cusi D, Felicita SC, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Delgado G, Demirkan A, Devuyst O, Dittrich K, Eckardt KU, Ehret G, Endlich K, Evans MK, Gansevoort RT, Gasparini P, Giedraitis V, Gieger C, Girotto G, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V; German Chronic Kidney Disease Study, Haller T, Hamet P, Harris TB, Hayward C, Hicks AA, Hofer E, Holm H, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Lewis RM, Ingelsson E, Jakobsdottir J, Jonsdottir I, Jonsson H, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kanai M, Kerr SM, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Krämer BK, Kronenberg F, Kubo M, Kühnel B, La Bianca M, Lange LA, Lehne B, Lehtimäki T; Lifelines Cohort Study, Liu J, Loeffler M, Loos RJF, Lyytikäinen LP, Magi R, Mahajan A, Martin NG, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Metspalu A, Milaneschi Y; V. A. Million Veteran Program, O’Donnell CJ, Wilson OD, Gaziano JM, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Müller-Nurasyid M, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O’Connell JR, Olafsson I, Padmanabhan S, Penninx BWJH, Perls T, Peters A, Pirastu M, Pirastu N, Pistis G, Polasek O, Ponte B, Porteous DJ, Poulain T, Preuss MH, Rabelink TJ, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rizzi F, Robino A, Rudan I, Krajcoviechova A, Cifkova R, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Salvi E, Schmidt H, Schmidt R, Shaffer CM, Smith AV, Smith BH, Spracklen CN, Strauch K, Stumvoll M, Sulem P, Tajuddin SM, Teren A, Thiery J, Thio CHL, Thorsteinsdottir U, Toniolo D, Tönjes A, Tremblay J, Uitterlinden AG, Vaccargiu S, van der Harst P, van Duijn CM, Verweij N, Völker U, Vollenweider P, Waeber G, Waldenberger M, Whitfield JB, Wild SH, Wilson JF, Yang Q, Zhang W, Zonderman AB, Bochud M, Wilson JG, Pendergrass SA, Ho K, Parsa A, Pramstaller PP, Psaty BM, Böger CA, Snieder H, Butterworth AS, Okada Y, Edwards TL, Stefansson K, Susztak K, Scholz M, Heid IM, Hung AM, Teumer A, Pattaro C, Woodward OM, Vitart V, Köttgen A.
Nat Genet. 2019 Oct;51(10):1459-1474. doi: 10.1038/s41588-019-0504-x. Epub 2019 Oct 2.
PMID: 31578528 [PubMed – indexed for MEDLINE] Free PMC Article 
Molecular Structure of the PKD Protein Complex Finally Solved.
Woodward OM, Watnick T.
Am J Kidney Dis. 2019 May;73(5):620-623. doi: 10.1053/j.ajkd.2018.12.022. Epub 2019 Jan 28. No abstract available. 
PMID: 30704879 [PubMed – indexed for MEDLINE]
  
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels.
Tin A, Li Y, Brody JA, Nutile T, Chu AY, Huffman JE, Yang Q, Chen MH, Robinson-Cohen C, Macé A, Liu J, Demirkan A, Sorice R, Sedaghat S, Swen M, Yu B, Ghasemi S, Teumer A, Vollenweider P, Ciullo M, Li M, Uitterlinden AG, Kraaij R, Amin N, van Rooij J, Kutalik Z, Dehghan A, McKnight B, van Duijn CM, Morrison A, Psaty BM, Boerwinkle E, Fox CS, Woodward OM, Köttgen A.
Nat Commun. 2018 Oct 12;9(1):4228. doi: 10.1038/s41467-018-06620-4.
PMID: 30315176 [PubMed – indexed for MEDLINE] Free PMC Article 
  
Three-dimensional in vitro models answer the right questions in ADPKD cystogenesis.
Dixon EE, Woodward OM.
Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F332-F335. doi: 10.1152/ajprenal.00126.2018. Epub 2018 Apr 25. Review.
PMID: 29693448 [PubMed – indexed for MEDLINE] Free PMC Article 
ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches.
Cleophas MC, Joosten LA, Stamp LK, Dalbeth N, Woodward OM, Merriman TR.
Pharmgenomics Pers Med. 2017 Apr 20;10:129-142. doi: 10.2147/PGPM.S105854. eCollection 2017. Review.
PMID: 28461764 [PubMed] Free PMC Article 
  
ABCG2: the molecular mechanisms of urate secretion and gout.
Woodward OM.
Am J Physiol Renal Physiol. 2015 Sep 15;309(6):F485-8. doi: 10.1152/ajprenal.00242.2015. Epub 2015 Jul 1. Review.
PMID: 26136557 [PubMed – indexed for MEDLINE] Free PMC Article 
Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier.
Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J.
J Control Release. 2014 Mar 28;178:8-17. doi: 10.1016/j.jconrel.2014.01.007. Epub 2014 Jan 14.
PMID: 24440664 [PubMed – indexed for MEDLINE] Free PMC Article 
Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules.
Woodward OM, Tukaye DN, Cui J, Greenwell P, Constantoulakis LM, Parker BS, Rao A, Köttgen M, Maloney PC, Guggino WB.
Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5223-8. doi: 10.1073/pnas.1214530110. Epub 2013 Mar 14.
PMID: 23493553 [PubMed – indexed for MEDLINE] Free PMC Article 
Transcomplementation by a truncation mutant of cystic fibrosis transmembrane conductance regulator (CFTR) enhances ΔF508 processing through a biomolecular interaction.
Cebotaru L, Woodward O, Cebotaru V, Guggino WB.
J Biol Chem. 2013 Apr 12;288(15):10505-12. doi: 10.1074/jbc.M112.420489. Epub 2013 Mar 5.
PMID: 23463513 [PubMed – indexed for MEDLINE] Free PMC Article 
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O’Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D’Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polašek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C.
Nat Genet. 2013 Feb;45(2):145-54. doi: 10.1038/ng.2500. Epub 2012 Dec 23.
PMID: 23263486 [PubMed – indexed for MEDLINE] Free PMC Article 
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T.
Nat Genet. 2012 Jul 15;44(8):904-9. doi: 10.1038/ng.2352.
PMID: 22797727 [PubMed – indexed for MEDLINE] Free PMC Article 
New advances in the pathophysiology of intestinal ion transport and barrier function in diarrhea and the impact on therapy.
Hoque KM, Chakraborty S, Sheikh IA, Woodward OM.
Expert Rev Anti Infect Ther. 2012 Jun;10(6):687-99. doi: 10.1586/eri.12.47. Review.
PMID: 22734958 [PubMed – indexed for MEDLINE]
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
Tin A, Woodward OM, Kao WH, Liu CT, Lu X, Nalls MA, Shriner D, Semmo M, Akylbekova EL, Wyatt SB, Hwang SJ, Yang Q, Zonderman AB, Adeyemo AA, Palmer C, Meng Y, Reilly M, Shlipak MG, Siscovick D, Evans MK, Rotimi CN, Flessner MF, Köttgen M, Cupples LA, Fox CS, Köttgen A; CARe and CHARGE Consortia.
Hum Mol Genet. 2011 Oct 15;20(20):4056-68. doi: 10.1093/hmg/ddr307. Epub 2011 Jul 18.
PMID: 21768215 [PubMed – indexed for MEDLINE] Free PMC Article 
A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells.
Liang L, Woodward OM, Chen Z, Cotter R, Guggino WB.
PLoS One. 2011;6(7):e21991. doi: 10.1371/journal.pone.0021991. Epub 2011 Jul 13.
PMID: 21765932 [PubMed – indexed for MEDLINE] Free PMC Article 
ABCG transporters and disease.
Woodward OM, Köttgen A, Köttgen M.
FEBS J. 2011 Sep;278(18):3215-25. doi: 10.1111/j.1742-4658.2011.08171.x. Epub 2011 Jun 13. Review.
PMID: 21554546 [PubMed – indexed for MEDLINE] Free PMC Article 
Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.
Woodward OM, Li Y, Yu S, Greenwell P, Wodarczyk C, Boletta A, Guggino WB, Qian F.
PLoS One. 2010 Aug 23;5(8):e12305. doi: 10.1371/journal.pone.0012305.
PMID: 20808796 [PubMed – indexed for MEDLINE] Free PMC Article 
Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal.
Kwon Y, Kim SH, Ronderos DS, Lee Y, Akitake B, Woodward OM, Guggino WB, Smith DP, Montell C.
Curr Biol. 2010 Sep 28;20(18):1672-8. doi: 10.1016/j.cub.2010.08.016.
PMID: 20797863 [PubMed – indexed for MEDLINE] Free PMC Article 
Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons.
Kim SH, Lee Y, Akitake B, Woodward OM, Guggino WB, Montell C.
Proc Natl Acad Sci U S A. 2010 May 4;107(18):8440-5. doi: 10.1073/pnas.1001425107. Epub 2010 Apr 19.
PMID: 20404155 [PubMed – indexed for MEDLINE] Free PMC Article 
Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion.
Hoque KM, Woodward OM, van Rossum DB, Zachos NC, Chen L, Leung GP, Guggino WB, Guggino SE, Tse CM.
J Gen Physiol. 2010 Jan;135(1):43-58. doi: 10.1085/jgp.200910339.
PMID: 20038525 [PubMed – indexed for MEDLINE] Free PMC Article 
Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease.
Li Y, Santoso NG, Yu S, Woodward OM, Qian F, Guggino WB.
J Biol Chem. 2009 Dec 25;284(52):36431-41. doi: 10.1074/jbc.M109.068916. Epub 2009 Oct 23.
PMID: 19854836 [PubMed – indexed for MEDLINE] Free PMC Article 
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
Woodward OM, Köttgen A, Coresh J, Boerwinkle E, Guggino WB, Köttgen M.
Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10338-42. doi: 10.1073/pnas.0901249106. Epub 2009 Jun 8.
PMID: 19506252 [PubMed – indexed for MEDLINE] Free PMC Article 
Nervous control of ciliary beating by Cl(-), Ca(2+) and calmodulin in Tritonia diomedea.
Woodward OM, Willows AO.
J Exp Biol. 2006 Jul;209(Pt 14):2765-73.
PMID: 16809467 [PubMed – indexed for MEDLINE] Free Article 
Dopamine modulation of Ca(2+) dependent Cl(-) current regulates ciliary beat frequency controlling locomotion in Tritonia diomedea.
Woodward OM, Willows AO.
J Exp Biol. 2006 Jul;209(Pt 14):2749-64.
PMID: 16809466 [PubMed – indexed for MEDLINE] Free Article 
Orientation and navigation relative to water flow, prey, conspecifics, and predators by the nudibranch mollusc Tritonia diomedea.
Wyeth RC, Woodward OM, Willows AO.
Biol Bull. 2006 Apr;210(2):97-108.
PMID: 16641515 [PubMed – indexed for MEDLINE]
Altered visual experience and acute visual deprivation affect predatory targeting by infrared-imaging Boid snakes.
Grace MS, Woodward OM.
Brain Res. 2001 Nov 23;919(2):250-8.
PMID: 11701137 [PubMed – indexed for MEDLINE]
 
Prey targeting by the infrared-imaging snake Python molurus: effects of experimental and congenital visual deprivation.
Grace MS, Woodward OM, Church DR, Calisch G.
Behav Brain Res. 2001 Feb 15;119(1):23-31.
PMID: 11164522 [PubMed – indexed for MEDLINE]